Prolonged Exposure to Air Pollution Tied to Disability in Seniors

TOPLINE:

Long-term exposure to air pollution, particularly particulate matter between 2.5 and 10 μm in diameter (PM_10-2.5), is associated with a higher risk of developing physical disability in older adults.

METHODOLOGY:

• Researchers conducted a cohort study to examine the effect of air pollution on physical disability in later life in a large cohort representative of older adults in the United States.
• They included 15,411 participants aged 65 years or older (mean age, 70.2 years; 55% women) who responded to the Health and Retirement Survey between 2000 and 2016.
• They estimated the 10-year average concentrations of various air pollutants, including PM ≤ 2.5 μm in diameter (PM_2.5), PM_10-2.5, nitrogen dioxide (NO₂), and ozone (O₃), at the participants’ homes using spatiotemporal prediction models.
• Physical disability was assessed on the index of limitations in activities of daily living such as dressing, walking across a room, bathing, eating, getting in and out of bed, and toileting.

TAKEAWAY:

• Long-term exposure to higher concentrations of PM_10-2.5 was associated with a 5% increase in risk for disability (adjusted hazard ratio [aHR], 1.05 per 4.9 μg/m³; P = .02).
• In contrast, long-term exposure to higher O₃ levels was associated with a lower risk for disability (aHR, 0.95 per 3.7 ppb; P = .03).
• No significant association was found for exposure to PM_2.5 or NO₂ and risk for disability.
• These associations were the strongest in adults aged 65-70 and 80-85 years.

IN PRACTICE:

“This finding suggests that reducing air pollution concentrations might help reduce the occurrence of [activities of daily living] disability in the population,” the authors of the study wrote.

SOURCE:

The study was led by Jiaqi Gao, PhD, of the University of Michigan, in Ann Arbor, Michigan, and was published online on September 26, 2024, in The Lancet Healthy Longevity.

LIMITATIONS:

The study did not differentiate between permanent and temporary transitions to disability, which may have affected the interpretation of the findings. The exclusion of individuals with missing data may have introduced selection bias. Moreover, errors in estimates of exposure could arise from the model used in the analysis.

DISCLOSURES:

This study was funded by the National Institute of Environmental Health Sciences and National Institute on Aging. Some authors received grants and consulting fees from the National Institutes of Health and other sources. One author reported serving as an associate editor of Discover Social Science and Health. The remaining authors declared no competing interests.

This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

SDGs, Targets, and Indicators

1. Which SDGs are addressed or connected to the issues highlighted in the article?

SDG 3: Good Health and Well-being

The issue of long-term exposure to air pollution and its impact on physical disability in older adults is connected to SDG 3, which aims to ensure good health and well-being for all ages. The article discusses the association between air pollution and the risk of developing physical disability in older adults.

SDG 11: Sustainable Cities and Communities

The issue of air pollution and its impact on health is also connected to SDG 11, which focuses on creating sustainable cities and communities. The article highlights the need to reduce air pollution concentrations to reduce the occurrence of disability in the population.

2. What specific targets under those SDGs can be identified based on the article’s content?

Target 3.9: By 2030, substantially reduce the number of deaths and illnesses from hazardous chemicals and air, water, and soil pollution and contamination.

The article’s content aligns with Target 3.9, as it discusses the association between air pollution (specifically particulate matter) and the risk of developing physical disability in older adults.

Target 11.6: By 2030, reduce the adverse per capita environmental impact of cities, including by paying special attention to air quality and municipal and other waste management.

The article’s content also aligns with Target 11.6, as it emphasizes the need to reduce air pollution concentrations to improve the health and well-being of the population.

3. Are there any indicators mentioned or implied in the article that can be used to measure progress towards the identified targets?

Indicator 3.9.1: Mortality rate attributed to household and ambient air pollution

The article does not explicitly mention this indicator, but it indirectly relates to the concept of mortality rate attributed to air pollution. The study’s findings suggest that long-term exposure to air pollution, specifically particulate matter, increases the risk of physical disability in older adults. By reducing air pollution, the occurrence of disability could be reduced, indirectly impacting the mortality rate attributed to air pollution.

Indicator 11.6.2: Annual mean levels of fine particulate matter (e.g., PM2.5 and PM10) in cities (population-weighted)

The article does not mention this indicator specifically, but it discusses the association between particulate matter (PM) and physical disability. Monitoring and reducing the annual mean levels of fine particulate matter in cities would contribute to achieving Target 11.6 and improving air quality.

4. SDGs, Targets, and Indicators

Source: medscape.com