Topoisomerase II inhibitor cures trypanosome infections

Topoisomerase II inhibitor cures trypanosome infections Nature.com

sdgtalks

Jul 19, 2023 - 12:00

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Topoisomerase II inhibitor cures trypanosome infections

RESEARCH HIGHLIGHT
19 July 2023

Sarah Crunkhorn

Sarah Crunkhorn

Trypanosome infections such as human African trypanosomiasis (HAT) and Chagas disease are vector-borne parasitic diseases transmitted by insects, that affect millions of individuals in tropical and subtropical regions. Therapeutic options are limited and infection can be fatal. Writing in Science, Rao et al. identify a new class of cyanotriazoles (CTs), which display potent and rapid trypanocidal activity in mouse models of HAT and Chagas disease.

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Topoisomerase II inhibitor cures trypanosome infections

Topoisomerase II inhibitor cures trypanosome infections Nature.com

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10. Are you advancing or impeding progress toward SDG No. 10: Reduce inequality among countries?

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